What S Wrong With My Mouse

What s Wrong With My Mouse  PDF
Author: Jacqueline N. Crawley
Publisher: John Wiley & Sons
ISBN: 0470119047
Size: 20.14 MB
Format: PDF, Kindle
Category : Science
Languages : en
Pages : 544
View: 1166

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Dr. Jacqueline N. Crawley, author of the First and Second Editions of What’s Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice,continues to field calls and e-mails from molecular geneticists who ask: how do I run behavioral assays to find out what’s wrong with my mouse? Turn to What’s Wrong with My Mouse? to discover the wealth of mouse behavioral tasks and to get the guidance you need to select the best methods and necessary controls. Chapters are organized by behavioral domain, including measurements of general health, motor functions, sensory abilities, learning and memory, feeding and drinking, reproductive, social, emotional, and reward behaviors in mutant mice. Throughout the chapters, new behavioral tasks and new research discoveries have been added, bringing the Second Edition up to date with the latest science. In addition, the Second Edition includes two new chapters: "Neurodevelopment and Neurodegeneration" discusses mouse behavioral tasks relevant to neurodevelopmental diseases, such as mental retardation and autism, and to neurodegenerative diseases, such as Alzheimers, Parkinsons, Huntingtons, and amyotrophic lateral sclerosis. "Putting It All Together" recommends strategies for optimizing a battery of behavioral phenotyping tests to address your specific hypotheses about gene functions. The final chapter, "The Next Generation," examines new and emerging technologies. Throughout the book, the use of behavioral testing equipment is illustrated with photographs, diagrams, and representative data. Examples of behavioral tasks successfully applied to transgenic and knockout mouse models are provided, as well as references to the primary literature and step-by-step methods protocols. These features, along with a comprehensive index, listings of database and vendor websites, and an extensive list of references, make this book a valuable and practical resource for students and researchers.

Neuro

Neuro PDF
Author: Nikolas Rose
Publisher: Princeton University Press
ISBN: 1400846331
Size: 45.39 MB
Format: PDF, ePub
Category : Social Science
Languages : en
Pages : 352
View: 5425

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How the new brain sciences are transforming our understanding of what it means to be human The brain sciences are influencing our understanding of human behavior as never before, from neuropsychiatry and neuroeconomics to neurotheology and neuroaesthetics. Many now believe that the brain is what makes us human, and it seems that neuroscientists are poised to become the new experts in the management of human conduct. Neuro describes the key developments—theoretical, technological, economic, and biopolitical—that have enabled the neurosciences to gain such traction outside the laboratory. It explores the ways neurobiological conceptions of personhood are influencing everything from child rearing to criminal justice, and are transforming the ways we "know ourselves" as human beings. In this emerging neuro-ontology, we are not "determined" by our neurobiology: on the contrary, it appears that we can and should seek to improve ourselves by understanding and acting on our brains. Neuro examines the implications of this emerging trend, weighing the promises against the perils, and evaluating some widely held concerns about a neurobiological "colonization" of the social and human sciences. Despite identifying many exaggerated claims and premature promises, Neuro argues that the openness provided by the new styles of thought taking shape in neuroscience, with its contemporary conceptions of the neuromolecular, plastic, and social brain, could make possible a new and productive engagement between the social and brain sciences. Copyright note: Reproduction, including downloading of Joan Miro works is prohibited by copyright laws and international conventions without the express written permission of Artists Rights Society (ARS), New York.

What S Wrong With My Snake

What s Wrong with My Snake  PDF
Author: John Rossi
Publisher: BowTie Press
ISBN: 1882770846
Size: 67.14 MB
Format: PDF, ePub, Docs
Category : Pets
Languages : en
Pages : 160
View: 3626

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This user-friendly home medical reference identifies and explains existing and potential problems in snakes. Find out how location of a cage can affect your snake's appetite, or how a snake can become "mouse shy." Learn how to identify and correct problems associated with maladaptation, burns, constipation, dehydration, skin lesions, diarrhea, improper shedding, lack of appetite, feeding frequency, overheating, parasites, mouth rot, reproductive failure, rodent injuries, respiratory problems, vomiting, weight loss, seizures, tremors, incoordination and just about anything else that may be commonly found with the captive care of snakes.

Evolution Of The House Mouse

Evolution of the House Mouse PDF
Author: Miloš Macholán
Publisher: Cambridge University Press
ISBN: 0521760666
Size: 30.62 MB
Format: PDF, Mobi
Category : Science
Languages : en
Pages : 526
View: 4576

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A detailed review of the evolutionary context necessary to interpret patterns and processes in the age of mouse genomics.

Novel Approaches To Studying Basal Ganglia And Related Neuropsychiatric Disorders

Novel Approaches to Studying Basal Ganglia and Related Neuropsychiatric Disorders PDF
Author: XIAO-HONG LU
Publisher: Academic Press
ISBN: 9780080953878
Size: 31.93 MB
Format: PDF, Mobi
Category : Science
Languages : en
Pages : 195
View: 7279

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Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume is a collection of articles covering Novel Approaches to Studying Basal Ganglia and Related Neuropsychiatric Disorders. Topics covered include molecular profiling of direct and indirect striatal medium spiny neurons, the role of epigenetics in development and function of basal ganglia and transgenic animal models for Parkinson's disease.

Behavioral Aspects Of Epilepsy

Behavioral Aspects of Epilepsy PDF
Author: Gregory L. Holmes, MD
Publisher: Demos Medical Publishing
ISBN: 9781934559888
Size: 78.34 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 264
View: 5179

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The field of epilepsy and behavior has grown considerably in the past number of years, reflecting advances in the laboratory and clinic. Behavioral Aspects of Epilepsy: Principles and Practice is the definitive text on epilepsy behavioral issues, from basic science to clinical applications, for all neurologists, psychosocial specialists, and researchers in the fields of epilepsy, neuroscience, and psychology/psychiatry. Behavioral aspects of epilepsy include a patient's experiences during seizures, his or her reaction during and between seizures, the frequency of episodes and what can be determined from the number of seizures. With contributions by dozens of leading international experts, this is the only book to cover all aspects of this critical emerging science. Adult and pediatric patients, animal models, and epilepsy surgery and its effects are all covered in detail. Behavioral Aspects of Epilepsy is the only source for up-to-date information on a topic that has significant and growing interest in the medical community. This comprehensive, authoritative text has a bench to bedside, approach that covers: The mechanisms underlying epilepsy and behavior Neurophysiologic function Neuropsychiatric and behavioral disorders in patients with epilepsy The effects of treatments and surgery on behavior Pediatric and adolescent epilepsy Disorders associated with epilepsy that impact behavior And much more

Comparative Medicine

Comparative Medicine PDF
Author:
Publisher:
ISBN:
Size: 19.23 MB
Format: PDF, Kindle
Category : Laboratory animals
Languages : en
Pages :
View: 650

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Molecular Mechanisms Influencing Aggressive Behaviours

Molecular Mechanisms Influencing Aggressive Behaviours PDF
Author: Gregory R. Bock
Publisher: John Wiley & Sons Incorporated
ISBN:
Size: 65.71 MB
Format: PDF, ePub
Category : Medical
Languages : en
Pages : 264
View: 7241

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This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular reference to possible implications for understanding human aggression. Chapters focus on the major current experimental issues in the study of aggression in humans and animals. The extensive discussions deal with specific problems of interpretation at the molecular level, as well as general issues relating to our understanding of human and animal aggression.

Neural Signaling

Neural Signaling PDF
Author: Edward J. Goetzl
Publisher: Wiley-Blackwell
ISBN:
Size: 48.74 MB
Format: PDF, ePub, Mobi
Category : Science
Languages : en
Pages : 280
View: 1723

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Low-molecular-weight chemicals, which are produced and secreted by neurons and a limited range of non-neural cells, are the major vehicles for communication of nerve cells with each other and with neurally controlled non-neural cells. Research over the past several decades has identified a wide spectrum of such neuromediators, delineated their structures, elucidated pathways of biosynthesis and biodegradation, and determined the processes of development and function that they influence physiologically. These results have revealed the nature of cellular receptors that recognize neuromediators selectively and the pathways that transduce signals from neuromediator-occupied receptors to the target cells. For most neuromediators and their receptors, pharmacological agonists and antagonists of high specificity also have been discovered or designed and synthesized. In the past decade, a broad range of animal models has been developed in which modern genetic methods have allowed overexpression and deletion of neuromediators and/or of their receptors for sophisticated analyses of their roles in normal physiology and some diseases. The availability of pharmacological agents directed to neuromediators or their receptors also has stimulated early studies of the involvement of these systems in some human diseases. At the same time as these revolutionary advances, most established conference series dedicated to this subject area have become narrower and have focused more sharply on individual neuromediators to permit deeper and more penetrating presentations and discussions. At this time, it seems appropriate to organize a volume that examines the conceptual, methodological, and practical progress in the field from broader biological and pathophysiological perspectives. This volume describes a new international conference in the integrated field of neuromediators that has no predecessors and is set in a biomedical context of possible diagnostic and therapeutic approaches. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member

Biobehavioral Stress Response

Biobehavioral Stress Response PDF
Author: International Society of Psychoneuroendocrinology. Congress
Publisher:
ISBN:
Size: 65.31 MB
Format: PDF
Category : Electronic books
Languages : en
Pages : 331
View: 5607

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Papers from a September 2003 meeting provide an opportunity to examine many of the popular assumptions about the biologic components of the stress response that confer distress or are likely to culminate in mental or physical pathology, and to replace these assumptions with findings that suggest a far more complex model of stress. The book draws attention to the lack of uniform biological and behavioral responses to stress, focusing instead on the multifaceted attributes of stressors and individual vulnerability and protective factors. There is no subject index. Annotation ©2004 Book News, Inc., Portland, OR (booknews.com).

Behavioral Genetics

Behavioral Genetics PDF
Author: Robert Plomin
Publisher: Macmillan
ISBN:
Size: 21.65 MB
Format: PDF
Category : Psychology
Languages : en
Pages : 532
View: 2938

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This book provides an overview of human and animal behavioral genetics and examines the crossroads where the fields of psychology, psychiatry, and genetics intersect.

Mac Answers

Mac Answers  PDF
Author: Bob LeVitus
Publisher: McGraw-Hill Osborne Media
ISBN:
Size: 41.79 MB
Format: PDF, Mobi
Category : Computers
Languages : en
Pages : 462
View: 5101

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A guide to the Macintosh computer explains how to do troubleshooting, install software, and upgrade programs, and answers commonly-asked questions such as "where can I find great freeware for my Mac?"

Bibliographic Index

Bibliographic Index PDF
Author:
Publisher:
ISBN:
Size: 50.90 MB
Format: PDF, ePub, Mobi
Category : Bibliographical literature
Languages : en
Pages : 26
View: 1514

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