Mitochondrial Function In Lung Health And Disease

Mitochondrial Function in Lung Health and Disease PDF
Author: Viswanathan Natarajan
Publisher: Springer
ISBN: 1493908294
Size: 76.78 MB
Format: PDF, Kindle
Category : Medical
Languages : en
Pages : 222
View: 7544

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Mitochondria, often referred to as the “powerhouses” of the cell, generate adenosine triphosphate (ATP) by oxidative phosphorylation or OXPHOS, and maintain cellular homeostasis. In addition to generating ATP, mitochondria are involved in regulation of cell cycle, proliferation, free radical production, innate immune responses and apoptosis. Mitochondrial Function in Lung Health and Disease fills the current gap in the literature and outlines the growing clinical relevance of mitochondrial dysfunction. Currently, there is no overview on the role of mitochondria in pulmonary diseases and this volume focuses on the mitochondrial metabolism, redox signaling, and mechanisms of mitochondrial pathways in lung injury, inflammation, repair and remodeling. Furthermore, in addition to their well-recognized role in cellular energy production and apoptosis, mitochondria appear to play a role in many respiratory diseases and lung cancer. Chapters are written by top notch researchers and clinicians and outline the evidence for mitochondrial biogenesis in inhalational lung injury, COPD and asthma.

Measuring Oxidants And Oxidative Stress In Biological Systems

Measuring Oxidants and Oxidative Stress in Biological Systems PDF
Author: Lawrence J. Berliner
Publisher: Springer Nature
ISBN: 303047318X
Size: 25.55 MB
Format: PDF, ePub
Category : Science
Languages : en
Pages : 237
View: 5679

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This book describes the methods of analysis and determination of oxidants and oxidative stress in biological systems. Reviews and protocols on select methods of analysis of ROS, RNS, oxygen, redox status, and oxidative stress in biological systems are described in detail. It is an essential resource for both novices and experts in the field of oxidant and oxidative stress biology.

Omega 3 Fatty Acids

Omega 3 Fatty Acids PDF
Author: Mahabaleshwar V. Hegde
Publisher: Humana Press
ISBN: 331940458X
Size: 40.88 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 610
View: 4856

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This volume argues for the importance of essential nutrients in our diet. Over the last two decades there has been an explosion of research on the relationship of Omega-3 fatty acids and the importance of antioxidants to human health. Expert authors discuss the importance of a diet rich in Omega-3 Fatty acids for successful human growth and development and for the prevention of disease. Chapters highlight their contribution to the prevention and amelioration of a wide range of conditions such as heart disease, diabetes, arthritis, cancer, obesity, mental health and bone health. An indispensable text designed for nutritionists, dietitians, clinicians and health related professionals, Omega-3 Fatty Acids: Keys to Nutritional Health presents a comprehensive assessment of the current knowledge about the nutritional effects of Omega-3 fatty acids and their delivery in foods.

Mitochondria In Health And Disease

Mitochondria in Health and Disease PDF
Author: Carolyn D. Berdanier
Publisher: CRC Press
ISBN: 1420028847
Size: 31.38 MB
Format: PDF, Kindle
Category : Medical
Languages : en
Pages : 640
View: 5110

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It was once assumed that mitochondrial diseases were rare and that few people were affected. As knowledge has grown about these organelles and their function, it became clear that mitochondrial malfunction could be linked to several chronic diseases. Diabetes has been associated with DNA mutation and can cause mutation itself. This text discusses findings involving the effects of disease on mitochondrial number, mitogenesis, and the base sequence of mitochondrial DNA. Experts discuss their study of mitochondria and what happens when it malfunctions. This book also explores the idea that mutated mitochondrial DNA can result in disease, and vice versa.

Pulmonary Vasculature Redox Signaling In Health And Disease

Pulmonary Vasculature Redox Signaling in Health and Disease PDF
Author: Yong-Xiao Wang
Publisher: Springer
ISBN: 3319632450
Size: 68.76 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 422
View: 6730

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The main goal of this book is to form a high-quality platform in which well-known and emerging pioneering basic, translational and clinical scientists can present their latest, exciting findings in the studies of redox signaling in the pulmonary vasculature. Content from outstanding investigators with unique expertise and skills of molecular and cell biology, biochemistry, physiology, pharmacology, biophysics, biotechnology and medicine will update our current out-of-date concepts with new knowledge. Rapidly increasing scientific studies have gathered a large volume of novel and important information on redox signaling in healthy and diseased pulmonary vasculature. This volume covers the need for a cohesive book to display state-of-the-art advances in the field. The second major aim of this book is to help direct future research. Redox signaling is a major molecular process involved in almost every physiologic cellular response in the pulmonary vasculature including energy metabolism, host defense, gene expression, contraction, proliferation, and migration. Aberrancy in this important signaling pathway leads to a critical role in the development of nearly all pulmonary diseases, such as pulmonary hypertension, cor pulmonale, pulmonary edema, and vasculitis, among others.

Fishman S Pulmonary Diseases And Disorders Fourth Edition

Fishman s Pulmonary Diseases and Disorders  Fourth Edition PDF
Author: Alfred Fishman
Publisher: McGraw Hill Professional
ISBN: 0071457399
Size: 61.65 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 2948
View: 2526

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A complete guide to the entire field of respiratory medicine--with all-new content and a streamlined new design A Doody's Core Title for 2011! First published in 1980, Fishman's Pulmonary Diseases and Disorders is the classic reference through which pulmonary physicians have gained a commanding look at the diagnosis and treatment of pulmonary diseases and disorders. Edited by the world's foremost authorities, Fishman's Pulmonary Diseases and Disorders covers exactly what you need to know about lung diseases and their management, including sleep-disordered breathing, COPD, emphysema, and lung cancer, as well as new technological advances and imaging techniques. This unparalleled two-volume resource begins with a compelling overview of up-to-date clinical perspectives, along with the scientific basis of lung function in health and disease. It then provides turnkey information on everything from respiratory disease signs and symptoms, to obstructive lung diseases, occupational and environmental disorders, and specific respiratory conditions such as infectious diseases of the lungs and acute respiratory failure. New to the Fourth Edition: Information on recent advancements in many clinically relevant areas of pulmonary medicine Update to the infectious diseases chapters that reflect current practice guidelines and recent antimicrobial developments Clearer connection between fundamental science concepts and clinical applications, which reflect current scientific research Latest information on sleep disorders Review of recent recommendations of the American Thoracic Society and European Respiratory Society for the accurate interpretation of pulmonary function tests Appendices that include a respiratory questionnaire, normal values, and commonly used terms & symbols

Olives And Olive Oil In Health And Disease Prevention

Olives and Olive Oil in Health and Disease Prevention PDF
Author: Victor R. Preedy
Publisher: Academic Press
ISBN: 9780080922201
Size: 28.75 MB
Format: PDF, ePub, Mobi
Category : Technology & Engineering
Languages : en
Pages : 1520
View: 3317

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Long used in sacred ceremonies and associated with good health, the nutritional and health promoting benefits of olives and olive oils have been proven by an ever-increasing body of science. From cardiovascular benefits to anti-microbial, anti-cancer, antioxidant activity and effects on macrophages and aptoptosis to cellular and pathophysiollogical process, olives and olive oils are proving important in many healthful ways. For example, reactive components in olive oils or olive oil by-products have now been isolated and identified. These include tyrosol, hydroxytyrosol, 3,4-dihydroxyphenyl acetic acid elenolic acid and oleuropein. Oleic acid is the main monosaturated fatty acid of olive oil. These have putative protective effects and modulate the biochemistry of a variety of cell types including those of the vascular system. Some but not all components have been characterised by their putative pharmacological properties. It is possible that usage of these aforementioned products may have beneficial application in other disease. However, in order for this cross-fertilization to take place, a comprehensive understanding of olives and olive oils is required. Finding this knowledge in a single volume provides a key resource for scientists in a variety of food an nutritional roles. Key Features: * Explores olives and olive oil from their general aspects to the detailed level of important micro-and micronutrients * Includes coverage of various methodologies for analysis to help scientists and chemists determine the most appropriate option for their own studies, including those of olive-related compounds in other foods * Relates, in a single volume resource, information for food and nutritional chemists, pharmaceutical scientists, nutritionists and dieticians * Presents information in three key categories: General aspects of olives an olive oils; Nutritional, pharmacological and metabolic properties of olives and olive oil; Specific components of olive oil and their effects on tissue and body systems

Hormones And The Heart In Health And Disease

Hormones and the Heart in Health and Disease PDF
Author: Leonard Share
Publisher: Springer Science & Business Media
ISBN: 1592597084
Size: 30.43 MB
Format: PDF, ePub
Category : Medical
Languages : en
Pages : 260
View: 7325

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The maintenance of arterial blood pressure and the distribution of blood flow to the various organs of the body depends on the control of the pumping action of the heart and of the resistance of the vascular beds in the individual organs in accordance with their metabolic needs. These controls are achieved through the integrated actions of circulat ing hormones, humoral factors that are synthesized and released in the heart and blood vessels, and the autonomic nervous system. The heart, however, is not only the target for the direct and indirect actions of a number of hormones and humoral factors, it is also an endocrine organ in the traditional sense, synthesizing and secreting into the circulation chemical factors that act at distant sites. In this treatise, Hormones and the Heart in Health and Disease, we interpret "endocrinology" broadly and consider traditional hormones as well as autocoids that are secreted by the heart or that act on it. In this overview, the relevant chapters are indicated in parentheses. The discovery of atrial natriuretic peptide (ANP; atrial natriuretic factor, ANF) in the 1980s indicated that the heart does indeed function as an endocrine organ in the classic sense. ANP (Chapter I) is synthesized in the heart and secreted into the circulation for actions on the kidney, where it is a potent natriuretic agent, and on the vasculature, where it causes vasodilation. ANP can also affect myocardial contractility.

Hiv And Respiratory Disease An Issue Of Clinics In Chest Medicine E Book

HIV and Respiratory Disease  An Issue of Clinics in Chest Medicine  E Book PDF
Author: Kristina Crothers
Publisher: Elsevier Health Sciences
ISBN: 145577149X
Size: 30.21 MB
Format: PDF, ePub, Mobi
Category : Medical
Languages : en
Pages : 214
View: 4135

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This issue of Clinics in Chest Medicine is Guest Edited by Kristina Crothers, MD from the University of Washington and will focus on HIV and Respiratory Disease. Article topics include Abnormalities in Host Defense, Antiretroviral Therapy and Lung Immunology, HIV associated Pneumonia, HIV associated Tuberculosis, HIV associated lung malignancies, and HIV associated COPD.

Lung Diseases New Insights For The Healthcare Professional 2011 Edition

Lung Diseases  New Insights for the Healthcare Professional  2011 Edition PDF
Author:
Publisher: ScholarlyEditions
ISBN: 1464904162
Size: 34.24 MB
Format: PDF, ePub, Mobi
Category : Medical
Languages : en
Pages : 61
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Lung Diseases: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Lung Diseases in a concise format. The editors have built Lung Diseases: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Lung Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Lung Diseases: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Liver A Complete Book On Hepato Pancreato Biliary Diseases E Book

Liver  A Complete Book on Hepato Pancreato Biliary Diseases   E Book PDF
Author: Mamun-Al Mahtab
Publisher: Elsevier Health Sciences
ISBN: 8131231577
Size: 41.93 MB
Format: PDF, Docs
Category : Medical
Languages : en
Pages : 666
View: 758

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The spectrum and etiology of liver diseases vary widely between East and West and hence the focus and experience of hepatologists also remain varied at two corners of the globe. Hepatology being perhaps one of the most flourishing and evolving discipline of medical sciences, a book with recent information written by experts from all over the world was much needed. The present book fulfills this need. The book will serve as a useful reference manual to consultants, postgraduate students, and residents of Hepatology, Gastroenterology, Internal Medicine, Pathology, Virology, and Preventive Medicine as well as undergraduate clinical medical students. Liver is a comprehensive book that discusses all aspects of diseases ranging from epidemiology to prognosis. This book is unique in its conception and presentation, as not only it provides new information but also offers a balanced and rational approach to diseases of liver, pancreas, and biliary system. One of the characteristic features of the book is inclusion of diseases of pancreas and separate chapters on important topics like cytokines and chemokines and apoptosis in liver diseases, as a sound background in these is essential for becoming a good specialist. It contains a chapter on evidence-based clinical practice in hepatology, which is the basis of modern clinical practice. It also includes a chapter on preventive aspects of hepato-biliary diseases keeping in mind that prevention of diseases is always preferred to cure. One of the unique features of this book is, it has contributors from all over the world.

The Human Body In Health And Illness

The Human Body in Health and Illness PDF
Author: Barbara L. Herlihy
Publisher: Saunders
ISBN:
Size: 42.16 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 555
View: 7355

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This full-color textbook presents fundamental anatomy and physiology knowledge in an accessible and engaging manner. A reader-friendly style links basic concepts to clinical examples, making the material approachable even for those with no prior instruction on the subject. It integrates up-to-date anatomy and physiology knowledge with relevant material on chemistry, genetics, and immunology, and correlates normal anatomy and physiology with common pathophysiologic conditions and pharmacologic mechanisms. (Includes a FREE SIMON website at: www.harcourthealth.com/SIMON/Herlihy)

Murray And Nadel S Textbook Of Respiratory Medicine E Book

Murray and Nadel s Textbook of Respiratory Medicine E Book PDF
Author: Robert J. Mason
Publisher: Elsevier Health Sciences
ISBN: 1437735533
Size: 27.52 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 2440
View: 4143

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Murray and Nadel’s Textbook of Respiratory Medicine has long been the definitive and comprehensive pulmonary disease reference. Robert J. Mason, MD now presents the fifth edition in full color with new images and highlighted clinical elements. The fully searchable text is also online at www.expertconsult.com, along with regular updates, video clips, additional images, and self-assessment questions. This new edition has been completely updated and remains the essential tool you need to care for patients with pulmonary disease. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Master the scientific principles of respiratory medicine and its clinical applications. Work through differential diagnosis using detailed explanations of each disease entity. Learn new subjects in Pulmonary Medicine including Genetics, Ultrasound, and other key topics. Grasp the Key Points in each chapter. Search the full text online at expertconsult.com, along with downloadable images, regular updates, more than 50 videos, case studies, and self-assessment questions. Consult new chapters covering Ultrasound, Innate Immunity, Adaptive Immunity, Deposition and Clearance, Ventilator-Associated Pneumonia. Find critical information easily using the new full-color design that enhances teaching points and highlights challenging concepts. Apply the expertise and fresh ideas of three new editors—Drs. Thomas R. Martin, Talmadge E. King, Jr., and Dean E. Schraufnagel. Review the latest developments in genetics with advice on how the data will affect patient care.