Biochips

Biochips PDF
Author: Wan-Li Xing
Publisher: Springer Science & Business Media
ISBN: 3662050927
Size: 71.48 MB
Format: PDF, Mobi
Category : Science
Languages : en
Pages : 134
View: 736

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This book brings together contributions from internationally renowned experts in the biochip field. The authors present not only their latest research work, but also discuss current trends in biochip technology. Specific topics range from microarray technology and its applications to lab-on-a-chip technology.

Design Automation Methods And Tools For Microfluidics Based Biochips

Design Automation Methods and Tools for Microfluidics Based Biochips PDF
Author: Jun Zeng
Publisher: Springer Science & Business Media
ISBN: 1402051239
Size: 51.23 MB
Format: PDF
Category : Technology & Engineering
Languages : en
Pages : 403
View: 3184

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Design Automation Methods and Tools for Microfluidics-Based Biochips deals with all aspects of design automation for microfluidics-based biochips. Experts have contributed chapters on many aspects of biochip design automation. Topics covered include: device modeling; adaptation of bioassays for on-chip implementations; numerical methods and simulation tools; architectural synthesis, scheduling and binding of assay operations; physical design and module placement; fault modeling and testing; and reconfiguration methods.

Integrated Biochips For Dna Analysis

Integrated Biochips for DNA Analysis PDF
Author: Robin Liu
Publisher: Springer Science & Business Media
ISBN: 9780387767598
Size: 35.96 MB
Format: PDF, ePub
Category : Medical
Languages : en
Pages : 202
View: 7511

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The objective of this book is to provide up-to-date coverage of some of the emerging developments in the field of integrated DNA biochips. It will prove a useful source of information for researchers in the field and for those who are just entering the field of biochip research.

Protein Arrays Biochips And Proteomics

Protein Arrays  Biochips and Proteomics PDF
Author: Joanna S. Albala
Publisher: CRC Press
ISBN: 9780203911129
Size: 61.34 MB
Format: PDF, ePub, Mobi
Category : Medical
Languages : en
Pages : 422
View: 2041

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From disease marker identification to accelerated drug development, Protein Arrays, Biochips, and Proteomics offers a detailed overview of current and emerging trends in the field of array-based proteomics. This reference focuses on innovations in protein microarrays and biochips, mass spectrometry, high-throughput protein expression, protein-prote

Digital Microfluidic Biochips

Digital Microfluidic Biochips PDF
Author: Krishnendu Chakrabarty
Publisher: CRC Press
ISBN: 1351837532
Size: 26.88 MB
Format: PDF, Mobi
Category : Technology & Engineering
Languages : en
Pages : 228
View: 4095

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Digital Microfluidic Biochips focuses on the automated design and production of microfluidic-based biochips for large-scale bioassays and safety-critical applications. Bridging areas of electronic design automation with microfluidic biochip research, the authors present a system-level design automation framework that addresses key issues in the design, analysis, and testing of digital microfluidic biochips. The book describes a new generation of microfluidic biochips with more complex designs that offer dynamic reconfigurability, system scalability, system integration, and defect tolerance. Part I describes a unified design methodology that targets design optimization under resource constraints. Part II investigates cost-effective testing techniques for digital microfluidic biochips that include test resource optimization and fault detection while running normal bioassays. Part III focuses on different reconfiguration-based defect tolerance techniques designed to increase the yield and dependability of digital microfluidic biochips. Expanding upon results from ongoing research on CAD for biochips at Duke University, this book presents new design methodologies that address some of the limitations in current full-custom design techniques. Digital Microfluidic Biochips is an essential resource for achieving the integration of microfluidic components in the next generation of system-on-chip and system-in-package designs.

Design And Testing Of Digital Microfluidic Biochips

Design and Testing of Digital Microfluidic Biochips PDF
Author: Yang Zhao
Publisher: Springer Science & Business Media
ISBN: 1461403707
Size: 14.13 MB
Format: PDF, ePub, Mobi
Category : Technology & Engineering
Languages : en
Pages : 204
View: 809

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This book provides a comprehensive methodology for automated design, test and diagnosis, and use of robust, low-cost, and manufacturable digital microfluidic systems. It focuses on the development of a comprehensive CAD optimization framework for digital microfluidic biochips that unifies different design problems. With the increase in system complexity and integration levels, biochip designers can utilize the design methods described in this book to evaluate different design alternatives, and carry out design-space exploration to obtain the best design point.

Biochips As Pathways To Drug Discovery

Biochips as Pathways to Drug Discovery PDF
Author: Gary Hardiman
Publisher: CRC Press
ISBN: 1420015605
Size: 20.48 MB
Format: PDF, Docs
Category : Medical
Languages : en
Pages : 386
View: 5112

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In the fiercely competitive pharmaceutical marketplace, your organization cannot afford to spend excess dollars developing drugs that will fail to get FDA approval or have profoundly poor characteristics. Biochips as Pathways to Drug Discovery takes a comprehensive look at how the industry faces these challenges, using new technologies such as biochips to reduce the cost of drug discovery and improve drug safety. The book explores the tools and skills required at each step of the discovery process when using biochips to determine biological outcomes. The authors provide an in-depth review of the clinical and pharmacogenomic relevance of biochips, ChIP-chip assays, and high-throughput approaches. They discuss how biochips are used to develop biomarkers in the drug discovery process, primarily for gene expression profiling and Single Nucleotide Polymorphism (SNP) analysis. The book includes coverage of experimental theory, quality control, clinical laboratory sampling considerations, database concepts, industrial laboratory design, and the analysis of the resultant large data sets. It discusses the application of biochips to the study of malaria, toxicogenomics, and SNPs, as well as intellectual property and market overviews. The book concludes with a comprehensive overview of how these chips are employed from early target discovery through preclinical toxicology and on through to pharmacogenomic and proof of concept studies in humans. Written in an easily accessible style, the breadth of coverage introduces the subject to those new to the field, while the depth of coverage forms a foundation for future work. The book gives you the knowledge required to leverage the technology into bona fide discoveries. Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.

Biochips And Microarrays

Biochips and Microarrays PDF
Author: Kewal K. Jain
Publisher:
ISBN: 9781859783375
Size: 38.35 MB
Format: PDF, Kindle
Category : Biochips
Languages : en
Pages : 160
View: 6226

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Biochip is a broad term indicating the use of microchip technology in molecular biology. DNA microarray is a rapid method of sequencing and analyzing genes. Microarray technology is becoming a central platform for functional genomics and has been applied to gene discovery, gene expression, detection of mutation or polymorphism and gene mapping. Biochip technology has an important role to play in pharmacogenomics and molecular diagnostics. This report decribes developments and evaluates their potential applications.

Biochip Technology

Biochip Technology PDF
Author: Jing Cheng
Publisher: CRC Press
ISBN: 0203305043
Size: 36.70 MB
Format: PDF, Docs
Category : Science
Languages : en
Pages : 350
View: 2031

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Biochip technology has experienced explosive growth in recent years and Biochip technology describes the basic manufacturing and fabrication processes and the current range of applications of these chips. Top scientists from the biochip industry and related areas explain the diverse applications of biochips in gene sequencing, expression monitoring, disease diagnosis, tumor examination, ligand assay and drug discovery.

Silicon Based Integrated Microarray Biochips For Biosensing And Biodetection Applications

Silicon based Integrated Microarray Biochips for Biosensing and Biodetection Applications PDF
Author: Lei Zhang
Publisher:
ISBN:
Size: 26.77 MB
Format: PDF, ePub, Mobi
Category : Science
Languages : en
Pages :
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The silicon-based integrated microarray biochip (IMB) is an inter-disciplinary research direction of microelectronics and biological science. It has caught the attention of both industry and academia, in applications such as deoxyribonucleic acid (DNA) and immunological detection, medical inspection and point-of-care (PoC) diagnosis, as well as food safety and environmental surveillance. Future biodetection strategies demand biochips with high sensitivity, miniaturization, integration, parallel, multi-target and even intelligence capabilities. In this chapter, a comprehensive investigation of current research on state-of-the-art silicon-based integrated microarray biochips is presented. These include the electrochemical biochip, magnetic tunnelling junction (MTJ) based biochip, giant magnetoresistance (GMR) biochip and integrated oscillator-based biochip. The principles, methodologies and challenges of the aforementioned biochips will also be discussed and compared from all aspects, e.g., sensitivity, fabrication complexity and cost, compatibility with silicon-based complementary metal-oxide-semiconductor (CMOS) technology, multi-target detection capabilities, signal processing and system integrations, et cetera In this way, we discuss future silicon-based fully integrated biochips, which could be used for portable medical detection and low cost PoC diagnosis applications.

Micro Electrode Dot Array Digital Microfluidic Biochips

Micro Electrode Dot Array Digital Microfluidic Biochips PDF
Author: Zipeng Li
Publisher: Springer
ISBN: 3030029646
Size: 53.81 MB
Format: PDF, Docs
Category : Technology & Engineering
Languages : en
Pages : 144
View: 4303

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This book provides an insightful guide to the design, testing and optimization of micro-electrode-dot-array (MEDA) digital microfluidic biochips. The authors focus on the characteristics specific for MEDA biochips, e.g., real-time sensing and advanced microfluidic operations like lamination mixing and droplet shape morphing. Readers will be enabled to enhance the automated design and use of MEDA and to develop a set of solutions to facilitate the full exploitation of design complexities that are possible with standard CMOS fabrication techniques. The book provides the first set of design automation and test techniques for MEDA biochips. The methods described in this book have been validated using fabricated MEDA biochips in the laboratory. Readers will benefit from an in-depth look at the MEDA platform and how to combine microfluidics with software, e.g., applying biomolecular protocols to software-controlled and cyberphysical microfluidic biochips.

Biochips And Medical Imaging

Biochips and Medical Imaging PDF
Author: Adam de la Zerda
Publisher: Wiley
ISBN: 9781118910504
Size: 25.90 MB
Format: PDF, ePub, Mobi
Category : Technology & Engineering
Languages : en
Pages : 450
View: 6361

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Intended to encourage professors to start a course on “Biochips and Medical Imaging,” this textbook covers state-of-the-art and emerging bio-sensors, biochips, and imaging of systems (including the endocrine system, the circulatory system and the immune system). Medical diagnostics are divided into biochips (in-vitro diagnostics) and medical and molecular imaging (in-vivo imaging). The course will includes in-depth examples of biochips in diagnosing cancer and cardiovascular diseases, and the role of in-vitro and in-vivo diagnostics in these fields. The book assumes zero biology knowledge and minimal math background.

Vlsi Circuits For Biomedical Applications

VLSI Circuits for Biomedical Applications PDF
Author: Krzysztof Iniewski
Publisher: Artech House
ISBN: 1596933186
Size: 52.85 MB
Format: PDF, Mobi
Category : Biomedical engineering
Languages : en
Pages : 452
View: 7613

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Supported with over 280 illustrations and over 160 equations, the book offers cutting-edge guidance on designing integrated circuits for wireless biosensing, body implants, biosensing interfaces, and molecular biology. You discover innovative design techniques and novel materials to help you achieve higher levels circuit and system performance.