Aging And Human Longevity

Aging and Human Longevity PDF
Author: M.-F. Schulz-Aellen
Publisher: Springer Science & Business Media
ISBN: 1461220068
Size: 54.15 MB
Format: PDF, Kindle
Category : Science
Languages : en
Pages : 284
View: 4796

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The proportion of elderly people continues to increase in the western world-nearly a quarter of the population will be over 65 years by the year 2050. Since aging is accompanied by an increase in diseases and by a deterioration in well-being, finding solutions to these social, medical and psychological problems is necessarily a major goal for society. Scientists and medical practitioners are therefore faced with the urgent task of increasing basic knowledge of the biological processes that cause aging. More resources must be put into this research in order to achieve better understanding of the cellular mechanisms that underlie the differences in life span between species and to answer the difficult questions of why some individuals age more quickly than others, and why some develop liver problems, some have heart problems, and others brain problems. The results of such a wide program of research will provide important information about the causes of many life-threatening and/ or debilitating diseases of old age; it will help find ways to prevent some of the ailments that result from aging, and it may well lead to discoveries enabling the prolongation of human life.

Aging Death And Human Longevity

Aging  Death  and Human Longevity PDF
Author: Christine Overall
Publisher: Univ of California Press
ISBN: 9780520938809
Size: 40.91 MB
Format: PDF, Mobi
Category : Philosophy
Languages : en
Pages : 276
View: 5796

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With the help of medicine and technology we are living longer than ever before. As human life spans have increased, the moral and political issues surrounding longevity have become more complex. Should we desire to live as long as possible? What are the social ramifications of longer lives? How does a longer life span change the way we think about the value of our lives and about death and dying? Christine Overall offers a clear and intelligent discussion of the philosophical and cultural issues surrounding this difficult and often emotionally charged issue. Her book is unique in its comprehensive presentation and evaluation of the arguments—both ancient and contemporary—for and against prolonging life. It also proposes a progressive social policy for responding to dramatic increases in life expectancy. Writing from a feminist perspective, Overall highlights the ways that our biases about race, class, and gender have affected our views of elderly people and longevity, and her policy recommendations represent an effort to overcome these biases. She also covers the arguments surrounding the question of the "duty to die" and includes a provocative discussion of immortality. After judiciously weighing the benefits and the risks of prolonging human life, Overall persuasively concludes that the length of life does matter and that its duration can make a difference to the quality and value of our lives. Her book will be an essential guide as we consider our social responsibilities, the meaning of human life, and the prospects of living longer.

Calorie Restriction Aging And Longevity

Calorie Restriction  Aging and Longevity PDF
Author: Arthur V. Everitt
Publisher: Springer Science & Business Media
ISBN: 9789048185566
Size: 50.65 MB
Format: PDF, ePub
Category : Medical
Languages : en
Pages : 323
View: 1631

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Food or calorie restriction has been shown in many short-lived animals and the rhesus monkey to prolong life-span. Life-long nutrition studies are not possible in humans because of their long survival. Studies over two to six years in healthy adult humans have, however, shown that a 20% reduction in food or calorie intake slows many indices of normal and disease-related aging. Thus, it is widely believed that long-term reduction in calorie or food intake will delay the onset of age-related diseases such as heart disease, diabetes and cancer, and so prolong life. Over the last 20 or more years there has been a progressive rise in food intake in many countries of the world, accompanied by a rising incidence of obesity. Thus our increasing food and calorie intake has been linked to the rising incidence of cardiovascular disease and diabetes in early adult life. It is accepted that overeating, accompanied by reduced physical exercise, will lead to more age-related diseases and shortening of life-span. The answer is to reduce our calorie intake, improve our diet, and exercise more. But calorie restriction is extremely difficult to maintain for long periods. How then can we solve this problem? Edited by a team of highly distinguished academics, this book provides the latest information on the beneficial effects of calorie restriction on health and life-span. This book brings us closer to an understanding at the molecular, cellular and whole organism level of the way forward.

Modulating Aging And Longevity

Modulating Aging and Longevity PDF
Author: S.I. Rattan
Publisher: Springer Science & Business Media
ISBN: 9781402013690
Size: 33.78 MB
Format: PDF, ePub
Category : Science
Languages : en
Pages : 333
View: 3996

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After decades of systematic collection of data describing age-related changes in organisms, organs, tissues, cells and macromolecules, biogerontologists are now in a position to construct general principles of ageing and explore various possibilities of intervention using rational approaches. While not giving serious consideration to the claims made by charlatans, it cannot be ignored that several researchers are making genuine attempts to test and develop various means of intervention for the prevention and treatment of age-related diseases, for regaining the functional abilities and for prolonging the lifespan of experimental organisms. This book provides the most up-to-date information and a critical evaluation of a variety of approaches being tried for modulating aging and longevity, including dietary supplementation with antioxidants, vitamins and hormones, genetic engineering, life-style alterations, and hormesis through mild stress. The goal of research on ageing is not to increase human longevity regardless of the consequences, but to increase active longevity free from disability and functional dependence.

The Biology Of Human Longevity

The Biology of Human Longevity PDF
Author: Caleb E. Finch
Publisher: Elsevier
ISBN: 9780080545943
Size: 35.40 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 640
View: 220

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Written by Caleb Finch, one of the leading scientists of our time, The Biology of Human Longevity: Inflammation, Nutrition, and Aging in the Evolution of Lifespans synthesizes several decades of top research on the topic of human aging and longevity particularly on the recent theories of inflammation and its effects on human health. The book expands a number of existing major theories, including the Barker theory of fetal origins of adult disease to consider the role of inflammation and Harmon's free radical theory of aging to include inflammatory damage. Future increases in lifespan are challenged by the obesity epidemic and spreading global infections which may reverse the gains made in lowering inflammatory exposure. This timely and topical book will be of interest to anyone studying aging from any scientific angle. Author Caleb Finch is a highly influential and respected scientist, ranked in the top half of the 1% most cited scientists Provides a novel synthesis of existing ideas about the biology of longevity and aging Incorporates important research findings from several disciplines, including Gerontology, Genomics, Neuroscience, Immunology, Nutrition

Aging And The Art Of Living

Aging and the Art of Living PDF
Author: Jan Baars
Publisher: JHU Press
ISBN: 1421407094
Size: 32.30 MB
Format: PDF, ePub, Mobi
Category : Medical
Languages : en
Pages : 304
View: 2436

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In this deeply considered meditation on aging in Western culture, Jan Baars argues that, in today’s world, living longer does not necessarily mean living better. He contends that there has been an overall loss of respect for aging, to the point that understanding and "dealing with" aging people has become a process focused on the decline of potential and the advance of disease rather than on the accumulation of wisdom and the creation of new skills. To make his case, Baars compares and contrasts the works of such modern-era thinkers as Foucault, Heidegger, and Husserl with the thought of Plato, Aristotle, Sophocles, Cicero, and other Ancient and Stoic philosophers. He shows how people in the classical period—less able to control health hazards—had a far better sense of the provisional nature of living, which led to a philosophical and religious emphasis on cultivating the art of living and the idea of wisdom. This is not to say that modern society’s assessments of aging are insignificant, but they do need to balance an emphasis on the measuring of age with the concept of "living in time." Gerontologists, philosophers, and students will find Baars' discussion to be a powerful, perceptive conversation starter.

Immunology Of Aging

Immunology of Aging PDF
Author: Ahmad Massoud
Publisher: Springer Science & Business Media
ISBN: 3642394957
Size: 37.13 MB
Format: PDF, Docs
Category : Medical
Languages : en
Pages : 406
View: 669

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The rapidity of scientific progress over the last few years guarantees the utility of this new collection of state-of-the-art reviews on the immunology of aging, which is the result of extensive collaboration of more than sixty of the greatest thinkers and scholars in the field, in cooperation with a number of junior colleagues. The book summarizes current knowledge on the cellular and molecular aspects of the aging immune system and their clinical relevance, providing insights into the effects of the aging process on susceptibilities to those diseases most common among elders. The retrieval strategies used to slow down the decline in the immune system in the elderly are another subject detailed extensively. By providing a broad overview of immunosenescence and its consequences, as well as their potential modulation, this book will fill a gap in a timely manner. It will be of value to all immunologists, whether novice or experienced, as well as geriatricians and epidemiologists.

Aging And Older Adulthood

Aging and Older Adulthood PDF
Author: Joan T. Erber
Publisher: John Wiley & Sons
ISBN: 1118340043
Size: 41.98 MB
Format: PDF, Docs
Category : Psychology
Languages : en
Pages : 504
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The third edition of this essential text has been updated and expanded with new material that reflects the most recent developments in the field, and explores our current understanding of a broad range of topics related to aging and older adulthood. Fresh edition includes updated content such as revised case histories and reworked material on key concepts and research applications Retains the winning format of the second edition, with chapter contents framed by individual histories Dual models add cohesiveness to the presentation of theory Thematic structure facilitates reader comprehension Instructor resources provided online upon publication at www.wiley.com/go/erber

Inflammation Advancing Age And Nutrition

Inflammation  Advancing Age and Nutrition PDF
Author: Irfan Rahman
Publisher: Academic Press
ISBN: 0123978076
Size: 17.39 MB
Format: PDF, Docs
Category : Technology & Engineering
Languages : en
Pages : 394
View: 3767

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The book provides a comprehensive overview to understanding the integrated impact of the concepts of cellular and molecular aspects, models, environmental factors, and lifestyle involved in premature aging. Additionally, it examines how functional food, dietary nutraceuticals or pharmacological compounds can reverse inflammation and premature aging based on personalized medicine. This book is a valuable resource for health professionals, scientists and researchers, nutritionists, health practitioners, students and for all those who wish to broaden their knowledge in the allied field. Includes models of aging, including worm, mouse and human Explores the relationship of inflammation with diseases, including ocular health, Alzheimer's and Parkinson's disease, and muscle health Encompasses a variety of lifestyle impacts, including diet, exercise and nutrition Includes suggested nutritional interventions

Brocklehurst S Textbook Of Geriatric Medicine And Gerontology E Book

Brocklehurst s Textbook of Geriatric Medicine and Gerontology E Book PDF
Author: Howard M. Fillit
Publisher: Elsevier Health Sciences
ISBN: 1437720757
Size: 59.77 MB
Format: PDF, Docs
Category : Medical
Languages : en
Pages : 1152
View: 2969

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Popular with generations of practitioners, Brocklehurst's Textbook of Geriatric Medicine and Gerontology has been the definitive reference of choice in the field of geriatric care. The new 7th Edition, by Howard M. Fillit, MD, Kenneth Rockwood, MD, and Kenneth Woodhouse, carries on this tradition with an increased clinical focus and updated coverage to help you meet the unique challenges posed by this growing patient population. Consistent discussions of clinical manifestations, diagnosis, prevention, treatment, and more make reference quick and easy, while over 255 illustrations compliment the text to help you find what you need on a given condition. Examples of the latest imaging studies depict the effects of aging on the brain, and new algorithms further streamline decision making. Emphasizes the clinical relevance of the latest scientific findings to help you easily apply the material to everyday practice. Features consistent discussions of clinical manifestations, diagnosis, prevention, treatment, and more that make reference quick and easy. Includes over 255 illustrations—including algorithms, photographs, and tables—that compliment the text to help you find what you need on a given condition. Provides summary boxes at the end of each chapter that highlight important points. Features the work of an expert author team, now led by Dr. Howard M. Fillit who provides an American perspective to complement the book’s traditional wealth of British expertise. Includes an expanded use of algorithms to streamline decision making. Presents more color images in the section on aging skin, offering a real-life perspective of conditions for enhanced diagnostic accuracy. Includes examples of the latest imaging studies to help you detect and classify changes to the brain during aging. Offers Grade A evidence-based references keyed to the relevant text.

Immunosenescence

Immunosenescence PDF
Author: Graham Pawelec
Publisher: Springer Science & Business Media
ISBN: 9780387768427
Size: 53.87 MB
Format: PDF
Category : Medical
Languages : en
Pages : 194
View: 3493

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Human immunosenescence contributes to morbidity and mortality in later life. Understanding the reasons for age-associated alterations to protective immunity in the elderly would ultimately improve and extend healthspan. The majority of the papers collected in this remarkable and timely volume address the mechanisms responsible for immune ageing in humans. They also consider what might be accomplished to redress the erosion of immune competence with age.

Decoding Longevity

Decoding Longevity PDF
Author: Bryant Villeponteau, Ph.D.
Publisher: Booktango
ISBN: 1468940597
Size: 23.54 MB
Format: PDF, Docs
Category : Health & Fitness
Languages : en
Pages :
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Have you ever wondered why we age and if you could slow its progression? In DECODING LONGEVITY, aging expert Dr. Bryant Villeponteau offers a full spectrum biological and genetic review of the aging process in layman's language. He condenses a wealth of practical information for those interested in extending their health and longevity, including dietary, exercise, and supplement recommendations that could add decades to your healthspan. Dr. Villeponteau looks in detail at the last 20 years of aging research, and explores future developments, including the exponential increases in technology that will provide powerful tools for extending healthy longevity over the next 20 to 40 years.